Darvish, who signed a six-year deal worth $56 million in January, has success with his mid-90s fastball, slider and cut-fastball against the Padres. He allowed two hits and threw 36 pitches, 26 of which were strikes.
The Rangers (2-2) got five consecutive two-out hits on their way to scoring four runs in the fourth inning off Padres pitcher Joe Wieland, a former Rangers prospect who was traded to San Diego on July 31 with pitcher Robbie Erlin for reliever Mike Adams.
Yorvit Torrealba had a two-run single in the inning. Former Padres infielder Alberto Gonzalez followed with a two-run double off Wieland. Gonzalez finished with three hits and three RBIs.
Greg Reynolds followed Darvish with two scoreless innings.
Jeff Suppan, who started the game for the Padres, tossed two scoreless innings. Suppan, 37, is in camp on a Minor League contract. He allowed one hit and one walk.
The Padres avoided a shutout when outfielder Blake Tekotte hit a two-run triple in the eighth inning.
Rangers up next: Closer-turned-starter Neftali Feliz will make his first Cactus League start of spring when he takes the hill Thursday for the Rangers against the White Sox at Surprise Stadium. Michael Kirkman, Neal Cotts, Joe Beimel, Yoshinori Tateyama, Mark Lowe and Joe Nathan are also scheduled to pitch. Robbie Ross, Justin Miller, Jake Brigham, Wilmer Font, Kevin De La Cruz and Fabio Castillo will pitch in Thursday's "B" game.
Padres up next:The Padres face the Giants at 12:05 p.m. PT on Thursday at the Peoria Sports Complex. Edinson Volquez makes his spring debut for the Padres and is set to throw two innings. Volquez, one of four players obtained from the Reds in the December deal, has worked closely camp with pitching coach Darren Balsley to get back to pounding the strike zone, something that mostly eluded him in 2011 in Cincinnati. Volquez will slide into the starting rotation somewhere for the Padres.